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C–H···O interaction
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C–H···O interaction : ウィキペディア英語版
C–H···O interaction
In chemistry, a C–H···O interaction represents a special type of weak hydrogen bond. Although weak, these hydrogen bonds are very important in nature,
since they occur in the structures of important biomolecules like amino acids, proteins, sugars, DNA and RNA.〔G. R. Desiraju, T. Steiner, The Weak Hydrogen Bond in Structural Chemistry and Biology, 1999, OxfordUniversity Press, Oxford (1999).〕 C–H...O interactions represent 20-25% of all hydrogen bonds in proteins.〔M. S. Weiss, Trends Biochem. Sci., 2001, 26, 521.〕
== History ==

The C–H···O interaction was discovered in 1937 by Samuel Glasstone. Glasstone studied properties of mixtures of acetone with different halogenated derivatives of hydrocarbons and realized that dipole moments of these mixtures differ from dipole moments of pure substances. He explained this by establishing the concept of C–H···O interactions.

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